For two *different* classes that don't work well together regardless of spec, my guesses would be:

- shaman + priest
- warrior + rogue

(It's ROGUE, damn it! R - O - G - U - E. Pet peeve.)

Warriors and rogues don't really help each other out much. Crowd controls like Sap that put "don't touch this" tags on mobs are the bane of at least one warrior's existence. Neither of them has any healing outside of food and first aid. Neither of them really buffs the other one outside of Battle Shout.

Shamans and priests aren't that good a combo either. At least until they level up quite a bit, shaman CC is just slows, and priest CC involves sending all of the mobs running crazy-wise and Ghod only knows what they'll aggro. Shaman buffs are largely melee oriented, especially at the lower levels. And, in this combo, the shaman will be in melee most of the time, putting spells out of reach, and using the meager tools they have to try to hold aggro against the priest.

Best combo for levelling in PvE? IMO it's shaman + warrior. The warrior gets a lot of value out of shaman buffs, holds aggro, and the shaman's heals, though not as valuable as other healing classes' at lower levels, are enough to pull the warrior through.

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