I have all of my cooldowns macroed together, but not to my arcane blast.

However, I do have arcane power and icy veins macroed to blast, but on a separate action bar.

One bar is my "trash" bar, and none of those spells are macroed. It does, however, include the cooldowns each pulled out separately for situations that require more specific timing.

The second action bar is my "boss" bar. On it I have my super cooldown of death macro (mirror image, icy veins, arcane power, and a trinket, iirc) as well as my macroed AB.

Otherwise, both bars are essentially the same, so that I don't confuse myself and nova where I should CS. ;-)

I agree that Mr. Belt has given some bad advice with respect to attaching all cooldowns to the main nuke. It's more important to manage cooldown synergy than to maximize uptime. That includes synergy with the your group (like heroism) and with fight mechanics (i.e. don't pop cooldowns right before boss enters a phase change where he is invincible for a few seconds).

This requires a lot more control than macroing cds to main nuke and forgetting about them. You should have a separate nuke button and only use it at the right time.