I can highly recommend Satrina's Buff Frames. If you can think of a way to set up your buffs, it can do it.

I too used SBF until 4.0.1 came out. Now there is no way to click off a buff which can be a major headache sometimes. Hopefully the devs figure out a way to do it now.

That's a restriction (or an oversight) at Blizzard's end. There's no buff addon beyond the default UI that lets you do that any more :(.

@pancakes

Elk's Buff Bars do it - by creating a button that pops up for you to click on. It works "good enough".

Prat is fantastic, but I stopped using SBF after Blizzard stopped allowing you to right-click remove buffs when using a buff/debuff addon.

Now I just use moveanything to shuffle them off to where I need them to be, and let PowerAuras cover anything I might have to worry about otherwise (Maelstrom Weapon, Druid Bleeds, Slice and Dice, things like that).

There's a new version of SBF incoming that allows you to click of buffs. In fact if your adventurous you can use the beta version now.

Don't confuse 'oversight' on blizzards part with addon coders laziness.