First step: get yourself Add-on Control Panel. It will allow you to turn add-ons off and on without having to log out each time. Very useful for add-ons that you don't use on every character.

After you get Add-on Control Panel, use it to turn off all your add-ons. Completely resize and position them, one at a time, to fit your needs. Dig deep into the customization options and see what it can really do. Raven, as mentioned above, can do so much, you'll be amazed at how many other add ons become redundant.

You have limited space, and poor eyesight, so think about something like omen. You really don't need it to show more than the top 2 threats, to make sure you are not one of them, at least when you're healing. Same with recount. Only show the top 2 or 3 people, and use your scroll wheel if you need to see lower. Things like that can be a space saver.

Make use of macros anyplace you can to get rid of some action bar buttons.

Finally, try using Ealign to properly line up and size your add ons for that neat, squared off look.

Good luck.

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