The Spirit of Harmony is going to be the limiting factor in a lot of craftable items in Mists of Pandaria. Just take a look at all the recipes it'll be a reagent for -- some 153 so far, and they haven't even finished designing the professions. The interesting part of this is that the Spirits (and the Motes you can turn into Spirits) are going to be bind on pickup, which means that you can't trade for them.
Does this means that you will not be able to level a profession up to the new maximum skill level without farming Spirits and Motes of Harmony yourself? Will it mean the end of readily available, entry-level crafted PvP and PvE blues?